Popular question: Does a vasectomy cause prostate cancer?

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Vasectomy Not Associated With Prostate Cancer

Urology – February 28, 2009 – Vol. 25 – No. 04

There is no association between prostate cancer and age at vasectomy or years since vasectomy.

Article Reviewed: Vasectomy and the Risk of Prostate Cancer. Holt SK, Salinas CA, Stanford JL: J Urol; 2008;180 (December): 2565-2568.

Background: The majority of the literature now has shown no association between vasectomy and prostate cancer. The effect of vasectomy on men with a family history of prostate cancer or on those who underwent a vasectomy at a young age or had an extended period of time since the procedure has been poorly studied due to small sample sizes and short study follow-up.

Objective: To assess the risk of prostate cancer in men by age and length of time to exposure from vasectomy to disease.

Design: Population-based, prostate cancer case-controlled study.

Participants: 1327 men aged 35 to 74 years residing in King County, Washington, with a diagnosis of prostate cancer.

Methods: Cases of prostate cancer were identified from the SEER database for this population. Structured in-person interviews were conducted. Eligible controls were identified by random digit telephone dialing. Analysis based on prostate cancer Gleason score and stage was performed. Analysis was also performed based on demographics, age, prostate cancer screening history (within the last 5 years), family history of prostate cancer, and vasectomy parameters.

Results: 1327 men were eligible for study from the SEER database; 1001 completed the personal questionnaire. In total, 1340 controls were identified, of which 942 were interviewed. The control population showed that men who had undergone vasectomy were older, white, married, non-smokers with higher income and education, and had undergone PSA screening. Of men with prostate cancer and controls, 36% had undergone a vasectomy. Mean number of years since vasectomy in cases and controls was 21.1 years. No significant association was seen between prostate cancer and vasectomy status, age at vasectomy, years since vasectomy, or year of vasectomy. There was no evidence of risk estimates across vasectomy parameters. Risk did not change if men with prostate cancer within 2 years of vasectomy and controls with no PSA screening within 5 years (n=136) were excluded.

Conclusions:

No association was found between prostate cancer and vasectomy, even in men who had a vasectomy performed at a young age or had an extended period of time since vasectomy.

Reviewer’s Comments: This paper is a well-conducted, large case-control study that answers the concern about possible limitations of previous work that reported the lack of association between prostate cancer and vasectomy. This criticism often indicated inadequate follow-up since vasectomy to make this claim. In this study, average time since vasectomy in cases of prostate cancer and controls was 21 years. Multiple variables were looked at including vasectomy in the face of prostate cancer family history and screening. This large study should end the criticism on previous work that did not answer the question of prostate cancer and time from vasectomy. (Reviewer–Ajay K. Nangia, MBBS).

Do probiotics help prevent stones?

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The above is a calcium oxalate stone in the ureteral orifice just about to fall into the bladder…no wonder they hurt. The green tint you see is the laser fiber beam which will be used to fragment the stone.

Probiotic Supplements Sold on Internet Unlikely to Benefit Stone Patients

Urology – July 30, 2015 – Vol. 32 – No. 12

Current probiotic supplements marketed to reduce oxalate stone formation do not contain the active ingredients advertised.

Article Reviewed: Analysis of Commercial Kidney Stone Probiotic Supplements. Ellis ML, Shaw KJ, et al: Urology; 2015;85 (March): 517-521.

Objective: To determine the levels of Oxalobacter formigenes and the oxalate-degrading ability in probiotic supplements (PRO-LAB from Toronto, Canada, and Oxalo from Hyderabad, India) marketed to reduce kidney stone recurrence in stone-forming patients.

Design: Prospective in-vitro study.

Methods: Probiotic supplements obtained from PRO-LAB and Oxalo were cultured in a number of different medias. Optical density was used to measure bacterial growth, while ion chromatography was used to measure loss of oxalate in media. Polymerase chain reaction (PCR) was used to determine organism species.

Results: No growth of oxalate-degrading organisms occurred. PCR showed that the PRO-LAB supplement contained Lactococcus lactisand Oxalo contained several Bacillus species and Lactobacillus plantarum.

Conclusions: Current probiotic supplements did not contain O formigenes or other oxalate-degrading organisms and are unlikely to benefit calcium oxalate kidney stone patients.

Reviewer’s Comments: Much work is being performed in an attempt to provide O formigenes as a probiotic supplement in hopes of reducing urinary oxalate excretion in calcium oxalate stone-forming patients. However, it has proven very difficult to get viable O formigenes organisms to the intended site for colonization in patients. The current marketed formulations over the Internet (PRO-LAB and Oxalo) have no resemblance to organisms containing oxalate-degrading properties. These probiotics are a waste of money for patients and they should not be recommended for use. This study reminds us to use caution in recommending or purchasing any product that is not regulated by the Food and Drug Administration since no quality measures are required for supplements and the product is often not as advertised.(Reviewer–David A. Duchene, MD).

Causes of white particles in your urine.

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This is a common question and is most often the result of a bladder infection. Not mentioned in the article as a cause is the change in the ph of the urine by certain foods that will create phosphate crystals. This is a benign situation but often times a concern to patients. Read More.

Dietary Tips for Boosting Male Fertility

Dietary Tips for Boosting Male Fertility

By: Urology Care Foundation | Posted on: 03 Mar 2017

Dietary Tips for Boosting Male Fertility

Diet can affect a man’s sperm, so if you’re trying to have a baby, make healthy choices when you eat!

Fruits and Vegetables: Eat plenty of leafy greens, purple and yellow vegetables, apples, oranges, kiwi, blueberries and melon.

Whole Grains: Easy ways to get enough whole grains include a bowl of oatmeal at breakfast, whole-grain bread at lunch and brown rice with dinner.

Low-Fat Dairy: Dairy products are high in important nutrients, such as calcium, vitamin D, potassium and protein. Good low-fat dairy choices include 1 cup of milk or yogurt or 1 ounce of cheese each day.

Protein: Some healthy sources of protein are: fish, turkey, chicken breast, beans, nuts, seeds and tofu.

Fats: Limit foods high in saturated fats, such as red meat, full-fat dairy products and fried foods. Instead, consume healthy fats, such as an ounce of walnuts or almonds, extra-virgin olive oil or avocado.

Common question: Does a vasectomy cause prostate cancer?

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Vasectomy Not Associated With Prostate Cancer

Urology – February 28, 2009 – Vol. 25 – No. 04

There is no association between prostate cancer and age at vasectomy or years since vasectomy.

Article Reviewed: Vasectomy and the Risk of Prostate Cancer. Holt SK, Salinas CA, Stanford JL: J Urol; 2008;180 (December): 2565-2568.

Background: The majority of the literature now has shown no association between vasectomy and prostate cancer. The effect of vasectomy on men with a family history of prostate cancer or on those who underwent a vasectomy at a young age or had an extended period of time since the procedure has been poorly studied due to small sample sizes and short study follow-up.

Objective: To assess the risk of prostate cancer in men by age and length of time to exposure from vasectomy to disease.

Design: Population-based, prostate cancer case-controlled study.

Participants: 1327 men aged 35 to 74 years residing in King County, Washington, with a diagnosis of prostate cancer.

Methods: Cases of prostate cancer were identified from the SEER database for this population. Structured in-person interviews were conducted. Eligible controls were identified by random digit telephone dialing. Analysis based on prostate cancer Gleason score and stage was performed. Analysis was also performed based on demographics, age, prostate cancer screening history (within the last 5 years), family history of prostate cancer, and vasectomy parameters.

Results: 1327 men were eligible for study from the SEER database; 1001 completed the personal questionnaire. In total, 1340 controls were identified, of which 942 were interviewed. The control population showed that men who had undergone vasectomy were older, white, married, non-smokers with higher income and education, and had undergone PSA screening. Of men with prostate cancer and controls, 36% had undergone a vasectomy. Mean number of years since vasectomy in cases and controls was 21.1 years. No significant association was seen between prostate cancer and vasectomy status, age at vasectomy, years since vasectomy, or year of vasectomy. There was no evidence of risk estimates across vasectomy parameters. Risk did not change if men with prostate cancer within 2 years of vasectomy and controls with no PSA screening within 5 years (n=136) were excluded.

Conclusions:

No association was found between prostate cancer and vasectomy, even in men who had a vasectomy performed at a young age or had an extended period of time since vasectomy.

Reviewer’s Comments: This paper is a well-conducted, large case-control study that answers the concern about possible limitations of previous work that reported the lack of association between prostate cancer and vasectomy. This criticism often indicated inadequate follow-up since vasectomy to make this claim. In this study, average time since vasectomy in cases of prostate cancer and controls was 21 years. Multiple variables were looked at including vasectomy in the face of prostate cancer family history and screening. This large study should end the criticism on previous work that did not answer the question of prostate cancer and time from vasectomy. (Reviewer–Ajay K. Nangia, MBBS).

 

Questions about a Vasectomy? Here’s a resource.

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Dr. McHugh answers vasectomy questions from patients all over the USA on vasectomy.com. If you click on the link below and then click on Q and A you’ll be directed to all of the questions he’s answered over the years. The site breaks down the categories to help navigate to a particular area of concern. If you have a vasectomy question you can post it on vasectomy.com under “Ask the Doctor” and the likelihood is that Dr. McHugh will be asked to answer it. Give it a whirl!

 Vasectomy.com 

Remember to then click on Q and A to get the archives of Dr. McHugh’s answers.